Phenylephrine Hydrochloride | Adrenergic Receptors | A1-adrenoceptor Agonist

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Cat.No.	Product Name
2838	(R)-(-)-Phenylephrine hydrochloride

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Phenylephrine hydrochloride

Chemical Name: (R)-(-)-1-(3-Hydroxyphenyl)-2-methylaminoethanol hydrochloride

Biological Activity:

α₁-adrenoceptor agonist; pK_i values are 5.86, 4.87 and 4.70 for α_1D, α_1B and α_1A receptors respectively.

Technical Data:

M.Wt:	203.67
Formula:	C₉H₁₃NO₂.HCl
Storage:	Desiccate at RT
Solubility:	Soluble to 100 mM in Water and to 100 mM in DMSO
Purity:	>99%
CAS No:	[61-76-7]

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis: View current batch

Product/Material Safety Data Sheet: View current batch

References:

Minneman et al (1994) Selectivity of agonists for cloned α₁-adrenergic receptor subtypes. Mol.Pharmacol. 46 929. Ford et al (1997) Pharmacological pleiotropism of the human recombinant α_1A-adrenoceptor: implications for α₁-adrenoceptor classification. Br.J.Pharmacol. 121 1127. Morton et al (2007) α_1A-adrenoceptors mediate contractions to phenylephrine in rabbit penile arteries. Br.J.Pharmacol. 150 112.

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Keywords: Phenylephrine Hydrochloride, Adrenergic Receptors, A1-adrenoceptor Agonist, Tocris Bioscience

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Adrenoceptor Pharmacology
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