Zinc Protoporphyrin IX | Oxygenases / Oxidases | Haem Oxygenase & Guanylyl Cyclase Inhibitor

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Cat.No.	Product Name
0746	Zinc protoporphyrin IX

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Zinc protoporphyrin IX

Chemical Name: 7,12-Diethenyl-3,8,13,17-tetramethyl-21H,23H-porphine-2 ,18-dipropionic acid, zinc complex

Biological Activity:

Inhibitor of haem oxygenase, which generates the putative neurotransmitter CO.

Technical Data:

M.Wt:	626.03
Formula:	C₃₄H₃₂N₄O₄Zn
Storage:	Store at RT
Solubility:	Soluble to 50 mM in DMSO
CAS No:	[15442-64-5]

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References:

Brune and Ullrich (1987) Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase. Mol.Pharmacol. 32 497. Verma et al (1993) Carbon monoxide a putative neural messenger. Science 259 381. Luo and Vincent (1994) Metalloporphyrins inhibit nitric oxide-dependent cGMP formation in vivo. Eur.J.Pharmacol.Mol.Pharmacol.Sect. 267 263. Grundemar and Ny (1997) Pitfalls using metalloporphyrins in carbon monoxide research. TiPS 18 193.

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Keywords: Zinc Protoporphyrin IX, Oxygenases / Oxidases, Haem Oxygenase & Guanylyl Cyclase Inhibitor, Tocris Bioscience

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