Zardaverine | Phosphodiesterases | PDE3 / 4 Inhibitor

Category:

Cat.No.	Product Name
1046	Zardaverine

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Zardaverine

Chemical Name: 6-[4-(Difluoromethoxy)-3-methoxyphenyl]-3(2H)-pyridazin one

Biological Activity:

Phosphodiesterase inhibitor, selective for PDE3 and 4 (IC₅₀ values are 0.5 and 0.8 μM respectively).

Technical Data:

M.Wt:	268.22
Formula:	C₁₂H₁₀F₂N₂O₃
Storage:	Store at RT
Solubility:	Soluble to 100 mM in DMSO
CAS No:	[101975-10-4]

Resources:

Certificate of Analysis / MSDS:

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References:

Kilian et al (1989) Is phosphodiesterase inhibition a relevant bronchospasmolytic principle? Agents Actions Suppl. 28 331. Galvan and Schudt (1990) Actions of the phosphodiesterase inhibitor zardaverine on guinea pig ventricular muscle. Naunyn-Schmied.Arch.Pharmacol. 342 221.

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Keywords: Zardaverine, Phosphodiesterases, PDE3 / 4 Inhibitor, Tocris Bioscience

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