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Category: Ion ChannelsarrowPotassium ChannelsarrowOther Potasium Channels
Cat.No. Product Name
0416 YS-035 hydrochloride  
Price and Availability

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YS-035 hydrochloride
Chemical Name: N,N-Bis-(3,4-dimethoxyphenylethyl)-N-methylamine hydrochloride

Biological Activity:

A Ca2+ blocker that strikingly prolongs cardiac action potentials by inhibiting pacemaker current and K+ outward currents.

Technical Data:

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M.Wt: 395.93
Formula: C21H29NO4.HCl
Storage: Desiccate at RT
Solubility: Soluble to 100 mM in Water
CAS No: [33978-72-2]

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    References:

    Deana et al (1984) Properties of a new calcium ion antagonist on cellular uptake and mitochondrial efflux of calcium ions. Biochem.J. 218 899. Berger et al (1991) Inhibition of potassium outward currents and pacemaker current in sheep cardiac Purkinje fibres by the verapamil derivative YS-035. Naunyn-Schmied.Arch.Pharmacol. 344 653.
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    Keywords: YS-035 Hydrochloride, Potassium Channels, Inhibits K+ Outward / Pacemaker Current, YS035 Hydrochloride, Tocris Bioscience
    Literature in this Area
    Signal Transduction Guide
    Signal Transduction Guide : An informative guide for all scientists working in: Cell cycle & apoptosis, Protein kinases & phosphatases, Ion channels, Calcium & lipid signaling, Cyclic nucleotides & G-proteins, Nitric oxide, & Signaling EnzymesA complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
    View PDF
    “I am grateful for your honesty and courtesy. The principles of Tocris are very different to that of your competitors who, in fact, have put our inhibitor on the market without any approval, exhibiting a pirate policy and a total absence of ethics..”
    Researcher, University of Pisa, Italy
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