W-5 Hydrochloride | Signal Transduction | Calmodulin Antagonist | W5 Hydrochloride

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Cat.No.	Product Name
0368	W-5 hydrochloride

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W-5 hydrochloride

Chemical Name: N-(6-Aminohexyl)-1-naphthalenesulfonamide hydrochloride

Biological Activity:

Calmodulin antagonist (inhibits Ca²⁺-calmodulin dependent PDE with an IC₅₀ of 240 μM).

Technical Data:

M.Wt:	342.88
Formula:	C₁₆H₂₂N₂O₂S.HCl
Storage:	Store at RT
Solubility:	Soluble to 50 mM in DMSO
CAS No:	[61714-25-8]

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References:

Hidaka et al (1981) Activity-structure relationship of calmodulin antagonists. Naphthalenesulfonamide derivatives. Mol.Pharmacol. 20 571. Hidaka et al (1981) N-(6-aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonist, inhibits cell proliferation. Proc.Natl.Acad.Sci.USA 78 4354. Hidaka and Tanaka (1983) Naphthalenesulfonamides as calmodulin antagonists. Methods Enzymol. 102 185.

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Keywords: W-5 Hydrochloride, Signal Transduction, Calmodulin Antagonist, W5 Hydrochloride, Tocris Bioscience

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