Vinpocetine | Sodium Channels | Na+ Channel Blocker

Category:

Cat.No.	Product Name
0757	Vinpocetine

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Vinpocetine

Chemical Name: (3a,16a)-Eburnamenine-14-carboxylic acid ethyl ester

Biological Activity:

Phosphodiesterase inhibitor, selective for PDE1 (IC₅₀ = 21 μM). Also blocks voltage-gated Na⁺ channels.

Technical Data:

M.Wt:	350.46
Formula:	C₂₂H₂₆N₂O₂
Storage:	Store at RT
Solubility:	Soluble to 50 mM in Ethanol and to 10 mM in DMSO
CAS No:	[42971-09-5]

Resources:

Certificate of Analysis / MSDS:

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References:

Merck Index 12 10128. Hagiwara et al (1984) Effect of vinpocetine on cyclic nucleotide metabolism in vascular smooth muscle. Biochem.Pharmacol. 33 453. Molnar and Erdo (1995) Vinpocetine is as potent as phenytoin to block voltage-gated Na⁺ channels in rat cortical neurons. Eur.J.Pharmacol. 273 303.

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Keywords: Vinpocetine, Sodium Channels, Na+ Channel Blocker, Tocris Bioscience

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