Vincristine Sulfate | Cytoskeleton & Motor Proteins | Disrupts Microtubules

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Cat.No.	Product Name
1257	Vincristine sulfate

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Vincristine sulfate

Chemical Name: 22-Oxovincaleukoblastine

Biological Activity:

Anticancer agent; microtubule disrupter. Induces apoptosis in human lymphoma cells.

Technical Data:

M.Wt:	923.04
Formula:	C₄₆H₅₆N₄O₁₀.H₂SO₄
Storage:	Desiccate at +4°C
Solubility:	Soluble to 100 mM in Water
CAS No:	[2068-78-2]

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References:

Jordan et al (1985) Comparison of the effects of vinblastine, vincristine, vindesine, and vinepidine on microtubule dynamics and cell proliferation in vitro. Cancer Res. 45 2741. Takano et al (1993) Apoptosis induced by microtubule disrupting drugs in cultured human lymphoma cells. Inhibitory effects of phorbol ester and zinc sulphate. Pathol.Res.Pract. 189 197. Wang et al (1999) The effect of antimicrotubule agents on signal transduction pathways of apoptosis. Cancer Chemother.Pharmacol. 44 355.

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Keywords: Vincristine Sulfate, Cytoskeleton & Motor Proteins, Disrupts Microtubules, Tocris Bioscience

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