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Category:
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Enzymes Transferases
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Cat.No.
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Product Name
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2988 |
VULM 1457
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Price and Availability
Click here for full price details of
VULM 1457
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Chemical Name:
N-[2,6-bis(1-Methylethyl)phenyl]-N'-[4-[(4-nitrophenyl)
thio]phenyl]urea |
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Biological Activity:
Acyl-CoA: cholesterol acyltransferase (ACAT)
inhibitor. Decreases cholesterol levels in the plasma and liver of
diabetic-hypercholesterolaemic rats.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Adameova et al
(2006) Protective effect of simvastatin and VULM 1457 in ischaemic-reperfused
myocardium of the diabetic-hypercholesterolemic rats. Pharmazie 61
807. Adameova et al (2007) The myocardial infarct size-limiting
and antiarrhythmic effects of acyl-CoA: cholesterol acyltransferase inhibitor
VULM 1457 protect the hearts of diabetic-hypercholesterolaemic rats against
ischaemia/reperfusion injury both in vitro and in vivo.
Eur.J.Pharmacol. 576 114. Vojtassakova et al (2007)
Effect of VULM 1457, an ACAT inhibitor, on serum lipid levels and on real time
red blood cell flow in diabetic and non-diabetic hamsters fed high
cholesterol-lipid diet. Gen.Physiol.Biophys. 26 254.
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Keywords: VULM 1457, Transferases, Acyl-CoA: Cholesterol Acyltransferase (ACAT) Inhibitor, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
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