VUF 5681 Dihydrobromide | Histamine Receptors | Potent H3 Receptor Silent Antagonist | VUF5681 Dihydrobromide

Category:

Cat.No.	Product Name
2493	VUF 5681 dihydrobromide

Price and Availability

Click here for full price details of
VUF 5681 dihydrobromide

Chemical Name: 4-[3-(1H-Imidazol-4-yl)propyl]piperidine dihydrobromide

Biological Activity:

Potent histamine H₃ receptor silent antagonist (pK_i = 8.35).

Technical Data:

M.Wt:	355.11
Formula:	C₁₁H₁₉N₃.2HBr
Storage:	Desiccate at RT
Solubility:	Soluble to 100 mM in Water and to 100 mM in DMSO

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis: View current batch

Product/Material Safety Data Sheet: View current batch

References:

Kitbunnadaj et al (2004) Identification of 4-(1H-imidazol-4(5)-ylmethyl)pyridine (immethridine) as a novel, potent, and highly selective histamine H3 receptor agonist. J.Med.Chem. 47 2414. Leurs et al (2005) The histamine H₃ receptor: from gene cloning to H₃ receptor drugs. Nat.Rev.Drug Discov. 4 107. Moreno-Delgado et al (2006) Constitutive activity of H₃ autoreceptors modulates histamine synthesis in rat brain through the cAMP/PKA pathway. Neuropharmacology 51 517.

View related products by Pharmacological Action or by Research Area

Keywords: VUF 5681 Dihydrobromide, Histamine Receptors, Potent H3 Receptor Silent Antagonist, VUF5681 Dihydrobromide, Tocris Bioscience

Literature in this Area

Scientific Reviews

Histamine Receptors
Download PDF

“Our laboratory loves dealing with Tocris and consider many of the compounds you sell to be far better quality than the compounds that we have received from other companies. Once again, thank you very much..”

Researcher, Albany Medical College, USA

New Products in this Area

	0721	Aminopotentidine
	H₂ antagonist
	2034	ROS 234 dioxalate
	Potent H₃ antagonist
	1857	Burimamide oxalate
	Mixed H₂/H₃ antagonist
	2577	Cetirizine dihydrochloride
	Selective H₁ antagonist
	2477	Proxyfan maleate
	High affinity H₃ ligand

for new product e-alerts

User ID
Password