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Category:
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7TM Receptors Adenosine ReceptorsAntagonists
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Cat.No.
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Product Name
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1359 |
VUF 5574
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Price and Availability
Click here for full price details of
VUF 5574
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Chemical Name:
N-(2-Methoxyphenyl)-N'-[2-(3-pyrindinyl)-4-quinazolinyl
]-urea |
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Biological Activity:
Potent, selective, competitive antagonist for the human adenosine
A3 receptor (Ki = 4 nM). Displays ³ 2500-fold selectivity over A1 and A2A
receptors.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Baraldi and Borea (2000) New potent and selective human adenosine
A3 receptor antagonists. TiPS 21 456. van
Muijlwijk-Koezen et al (2000) Isoquinoline and quinazoline urea
analogues as antagonists for the human adenosine A3 receptor.
J.Med.Chem. 43 2227.
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or by Research Area
Keywords: VUF 5574, Adenosine Receptors, Potent, Selective HA3 Antagonist, VUF5574, Tocris Bioscience
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| “I am grateful for your honesty and courtesy. The principles of Tocris are very different to that of your competitors who, in fact, have put our inhibitor on the market without any approval, exhibiting a pirate policy and a total absence of ethics..” Researcher, University of Pisa, Italy |
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