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Category:
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7TM Receptors Adrenergic ReceptorsAlpha-2 ReceptorsAgonists
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Cat.No.
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Product Name
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2466 |
UK 14,304 tartrate
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Price and Availability
Click here for full price details of
UK 14,304 tartrate
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Chemical Name:
5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline tartrate |
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Biological Activity:
Water-soluble, full α2 adrenergic agonist.
Centrally active following systemic administration in vivo.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Cambridge (1981) UK-14,304, a potent and selective alpha2-gonist for the
characterisation of alpha-adrenoceptor subtypes. Eur.J.Pharmacol. 72
413. Andorn et al (1988) Specific [3H]UK-14,304 binding in human cortex occurs at multiple high affinity
states with α2-adrenergic selectivity and different affinities for GTP. Life Sci. 43
1805. Macdonald et al (1997) Gene trageting - homing in on α2-adrenoceptor-subtype
function. TiPS 18 211. Chopin et al (1999) Effects
of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats
with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway.
J.Pharmacol.Exp.Ther. 288 798.
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Keywords: UK 14,304 Tartrate, Adrenergic Receptors, Water-soluble Form Of Cat. No. 0425, UK14,304 Tartrate, Tocris Bioscience
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