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Category: 7TM ReceptorsarrowAdrenergic ReceptorsarrowAlpha-2 ReceptorsarrowAgonists
Cat.No. Product Name
0425 UK 14,304  
Price and Availability

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UK 14,304
Chemical Name: 5-Bromo-6-(2-imidazolin-2-ylamino)quinoxaline

Biological Activity:

Full α2 adrenergic agonist. Centrally active following systemic administration in vivo.

Technical Data:

Click here for more information on batch specific data
M.Wt: 292.14
Formula: C11H10BrN5
Storage: Store at RT
Solubility: Soluble to 100 mM in DMSO
CAS No: [59803-98-4]

Resources:

  • Certificate of Analysis / MSDS:

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    References:

    Andorn et al (1988) Specific [3H]UK-14,304 binding in human cortex occurs at multiple high affinity states with α2-adrenergic selectivity and different affinities for GTP. Life Sci. 43 1805. Macdonald et al (1997) Gene trageting - homing in on α2-adrenoceptor-subtype function. TiPS 18 211. Chopin et al (1999) Effects of alpha-2 adrenoceptor agonists and antagonists on circling behavior in rats with unilateral 6-hydroxydopamine lesions of the nigrostriatal pathway. J.Pharmacol.Exp.Ther. 288 798.
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    Keywords: UK 14,304, Adrenergic Receptors, A2 Agonist , UK14,304, Tocris Bioscience

    Literature in this Area
    Scientific Reviews
    Adrenoceptor Pharmacology
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