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Category: 7TM ReceptorsarrowDopamine ReceptorsarrowD2-like ReceptorsarrowAntagonists
Cat.No. Product Name
0775 (+)-UH 232 maleate  
Price and Availability

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(+)-UH 232 maleate
Chemical Name: cis-(+)-5-Methoxy-1-methyl-2-(di-N-propylamino)tetralin maleate

Biological Activity:

D2-like autoreceptor antagonist, and D3 partial agonist

Technical Data:

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M.Wt: 391.51
Formula: C18H29NO.C4H4O4
Storage: Store at RT
Solubility: Soluble to 50 mM in Ethanol and to 50 mM in Water
CAS No: [95999-12-5]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
    Product/Material Safety Data Sheet: View current batch

    References:

    Johansson et al (1985) Novel dopamine receptor agonists and antagonists with preferential action on autoreceptors. J.Med.Chem. 28 1049. Svensson et al (1986) (+)-AJ 76 and (+)-UH 232: central stimulants acting as preferential dopamine autoreceptor antagonists. Naunyn-Schmied.Arch.Pharmacol. 334 234. Griffon et al (1995) The preferential dopamine D3 receptor ligand, (+)-UH 232, is a partial agonist. Eur.J.Pharmacol. 282 R3. Hall and Strange (1997) Evidence that antipsychotic drugs are inverse agonists at D2 dopamine receptors. Br. J. Pharmacol. 121 731.
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    Keywords: (+)-UH 232 Maleate, Dopamine Receptors, D2-like Autoreceptor Antagonist. D3 Partial Agonist. , UH232 Maleate, Tocris Bioscience

    Literature in this Area
    Scientific Reviews
    Dopamine Receptors
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