Tocris Bioscience
Welcome to Tocris

| Advanced Search
Home Products Technical Support Customer Support Literature Custom Synthesis
Category: 7TM ReceptorsarrowOpioid ReceptorsarrowKappa ReceptorsarrowAgonists
Cat.No. Product Name
0471 (+)-U-50488 hydrochloride  
Price and Availability

Click here for full price details of
(+)-U-50488 hydrochloride
Chemical Name: trans-(+)-3,4-Dichloro-N-methyl-N-[2-(1-pyrrolidinyl)-c yclohexyl]benzeneacetamide hydrochloride

Biological Activity:

Less active enantiomer of (±)-U-50488 (Cat. No. 0495).

Technical Data:

Click here for more information on batch specific data
M.Wt: 405.79
Formula: C19H26Cl2N2O.HCl
Storage: Store at RT
Solubility: Soluble to 50 mM in Water
CAS No: [67198-17-8]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    De Costa et al (1987) Synthesis and absolute configuration of optically pure enantiomers of a κ-opioid receptor selective antagonist. FEBS Lett. 223 335.

    View related products by Pharmacological Action or by Research Area

    Keywords: (+)-U-50488 Hydrochloride, Opioid Receptors, Less Active Enantiomer Of Cat. No. 0495, U50488 Hydrochloride, Tocris Bioscience

    Literature in this Area
    Scientific Reviews
    Opioid Receptors
    Download PDF
    Featured New Product
    Selective NOP Antagonist
    2598   (±)-J 113397
    Potent and selective nociceptin / orphanin FQ (NOP, ORL1) receptor antagonist (IC50 values are 2.3,1400, 2200 and > 10000 nM for NOP, κ, μ and δ-opioid receptors respectively). Inhibits nociceptin / orphanin FQ-induced hyperalgesia in the mouse tail-flick test.
    View all Featured New Products
    New Products in this Area

     2965Diprenorphine
     Non-selective opioid antagonist
     2598(±)-J 113397
     Potent and selective NOP antagonist
     2601Cyprodime hydrochloride
     Selective μ antagonist
     2508Trap 101
     Potent and selective NOP antagonist
    Sign-up for new product e-alerts
    Log In / Register

    User ID
    Password
    If you are not registered with us Create Account