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Category:
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Enzyme-Linked Receptors Receptor Tyrosine Kinases (RTKs)EGFR
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Cat.No.
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Product Name
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0579 |
Tyrphostin B44, (+) enantiomer
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Price and Availability
Click here for full price details of
Tyrphostin B44, (+) enantiomer
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Chemical Name:
(S)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylet
hyl)-2-propenamide |
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Biological Activity:
Epidermal growth factor receptor (EGFR) kinase inhibitor (IC50
= 0.86 μM). Slightly less active
than the (-) enantiomer (Cat. No. 0578).
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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References:
Gazit et al (1991) Tyrphostins. 2. Heterocyclic and α-substituted
benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and
ErbB2/neu tyrosine kinases. J.Med.Chem. 34 1896.
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View related products by Pharmacological Action
or by Research Area
Keywords: Tyrphostin B44, (+) Enantiomer, Receptor Tyrosine Kinases (RTKs), EGFR-kinase Inhibitor, Tocris Bioscience
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Literature in this Area Cancer Research Guide | Our unique collection of more than 300 products related to cancer research, including the very latest exclusive research tools. | | Request Copy / View PDF |
Product Feature
Kinase Inhibitors
Key kinase Inhibitors available from Tocris include:
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