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Category:
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Enzyme-Linked Receptors Receptor Tyrosine Kinases (RTKs)EGFR
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Cat.No.
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Product Name
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0578 |
Tyrphostin B44, (-) enantiomer
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Price and Availability
Click here for full price details of
Tyrphostin B44
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Chemical Name:
(R)-(E)-2-Cyano-3-(3',4'-dihydroxyphenyl)-N-(1-phenylet
hyl)-2-propenamide |
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Biological Activity:
Potent inhibitor of epidermal growth factor receptor (EGFR) kinase
(IC50 = 0.4 μM), more active than the
(+) enantiomer (Cat. No. 0579). Selective over Her2-neu.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
Certificate of Analysis is currently unavailable on-line. Please contact Customer Service
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References:
Gazit et al (1991) Tyrphostins. 2. Heterocyclic and α-substituted benzylidenemalononitrile
tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine
kinases. J.Med.Chem. 34 1896.
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View related products by Pharmacological Action
or by Research Area
Keywords: Tyrphostin B44, Receptor Tyrosine Kinases (RTKs), EGFR-kinase Inhibitor, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
Product Feature
Kinase Inhibitors
Key kinase Inhibitors available from Tocris include:
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