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Category: 7TM ReceptorsarrowAdenosine ReceptorsarrowAntagonists
Cat.No. Product Name
2795 Theophylline
Price and Availability

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Theophylline
Chemical Name: 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione

Biological Activity:

Bronchodilator, anti-inflammatory and immunomodulator. Antagonises adenosine receptors and is a weak nonselective inhibitor of phosphodiesterases (PDEs).

Technical Data:

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M.Wt: 180.16
Formula: C7H8N4O2
Storage: Store at RT
Solubility: Soluble to 25 mM in Water and to 100 mM in DMSO
Purity: >99%
CAS No: [58-55-9]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Coward et al (1998) Asthma, adenosine, mast cells and theophylline. Clin.Exp.Allery 28 Suppl.3 42. Page (1999) Recent advances in our understanding of the use  of theophylline in the treatment of asthma. J.Clin.Pharmacol. 39 237. Barnes (2003) Theophylline. New perspectives for an old drug. Am.J.Respir.Care Med. 167 813.
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    Keywords: Theophylline, Adenosine Receptors, Adenosine Receptor Antagonist; Bronchodilator, Tocris Bioscience

    Literature in this Area
    Scientific Reviews
    Nucleotide & Nucleoside Receptors
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