Tocris Bioscience
Welcome to Tocris

| Advanced Search
Home Products Technical Support Customer Support Literature Custom Synthesis
Category: Ion ChannelsarrowSodium ChannelsarrowVoltage-gated Sodium Channels
Cat.No. Product Name
1069 Tetrodotoxin citrate
Alternative name(s): TTx
Price and Availability

Click here for full price details of
Tetrodotoxin citrate
Chemical Name: Octahydro-12-(hydroxymethyl)-2-imino-5,9:7,10a-dimethan o-10aH-[1,3]dioxocino[6,5-d]pyrimidine-4,7,10,11,12-pen tol citrate

Biological Activity:

Highly selective, reversible sodium channel blocker; citrate salt of tetrodotoxin.

Technical Data:

Click here for more information on batch specific data
M.Wt: 319.27
Formula: C11H17N3O8
Storage: Desiccate at -20°C
Solubility: Soluble to 100 mM in Water
CAS No: [18660-81-6]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    For specific/earlier batch please select:  
    Product/Material Safety Data Sheet: View current batch
    For specific/earlier batch please select:  

    References:

    Merck Index 12 9382. Kao (1972) Pharmacology of tetrodotoxin and saxitoxin. Fed.Proc. 31 1117. Kao (1986) Structure-activity relations of tetrodotoxin, saxitoxin, and analogues. Ann.N.Y.Acad.Sci. 479 52. Gleitz et al (1996) The protective action of tetrodotoxin and (±)-kavain on anaerobic glycolysis, ATP content and intracellular Na+ and Ca2+ of anoxic brain vesicles. Neuropharmacology 35 1743.
    View related products by Pharmacological Action or by Research Area

    Keywords: Tetrodotoxin Citrate, Sodium Channels, Citrate Salt Of Cat. No. 1078, TTx, Tocris Bioscience

    Literature in this Area
    Signal Transduction Guide
    Signal Transduction Guide : An informative guide for all scientists working in: Cell cycle & apoptosis, Protein kinases & phosphatases, Ion channels, Calcium & lipid signaling, Cyclic nucleotides & G-proteins, Nitric oxide, & Signaling EnzymesA complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
    View PDF
    Purity To Rely On
    When choosing reagents for an experiment, the prime consideration is often to obtain the highest quality products available.

    Unlike other suppliers, our in-house QC team carry out multiple analytical tests to thoroughly assess the purity of our reagents before they are offered for sale.

    This accurate purity data is available on a batch-specific basis for every product via our website. At Tocris we work hard to ensure that we always supply to the highest possible standards of purity.
    New Products in this Area

     3057Lidocaine
     Na+ channel blocker
     2642Co 102862
     State-dependent Na+ channel blocker; anticonvulsant
     2596Mexiletine hydrochloride
     Na+ channel blocker, antiarrhythmic agent
    Sign-up for new product e-alerts
    Log In / Register

    User ID
    Password
    If you are not registered with us Create Account