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Category:
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Ion Channels Other Channel Modulators
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Cat.No.
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Product Name
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2906 |
TRO 19622
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Price and Availability
Click here for full price details of
TRO 19622
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Chemical Name:
Cholest-4-en-3-one oxime |
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Biological Activity:
Neuroprotective and
neuroregenerative compound. Rescues motor neurons from axotomy-induced cell
death and promotes nerve regeneration following sciatic nerve crush in vivo.
Binds directly to two components of the mitochondrial permeability pore, the
voltage-dependent anion channel (VDAC) and translocator protein.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Bordet et al
(2007) Identification and characterization of cholest-4-en-3-one, oxime
(TRO19622), a novel drug candidate for amyotrophic lateral sclerosis.
J.Pharmacol.Exp.Ther. 322 709.
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View related products by Pharmacological Action
or by Research Area
Keywords: TRO 19622, Other Channel Modulators, Binds Voltage-dependent Anion Channel (VDAC), TRO19622, Tocris Bioscience
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Literature in this Area Signal Transduction Guide | A complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes. | | View PDF |
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