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Category:
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Cellular Processes and Components ApoptosisOther Apoptosis
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Biological Activity:
VGF-derived peptide; spans residues 556-576 of
the precursor sequence. Protects cerebellar granule cells (CGCs) from serum and
potassium deprivation-induced apoptosis. Increases energy expenditure and
prevents early phase diet-induced diabetes.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Bartolomucci et al (2006)
TLQP-21, a VGF-derived peptide, increases energy expenditure and prevents the
early phase of diet-induced obesity. Proct.Natl.Acad.Sci. USA 103
14584. Jethwa et al (2007) VGF-derived peptide, TLQP-21,
regulates food intake and body weight in Siberian hamsters. Endocrinol. 148
4044. Severini et al (2008) TLQP-21, a neuroendocrine VGF-derived
peptide, prevents cerebellar granule cell death induced by serum and potassium
deprivation. J.Neurochem. 104 534.
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Keywords: TLQP 21, Apoptosis, VGF-derived Peptide, Tocris Bioscience
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