TFLLR-NH2 | Peptides (Cardiovascular) | PAR1-activating Peptide

Category:

Cat.No.	Product Name
1464	TFLLR-NH₂

Price and Availability

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TFLLR-NH2

Biological Activity:

Peptide derived from the protease-activated receptor-1 (PAR₁) that acts as a PAR₁ selective agonist (EC₅₀ = 1.9 μM). Stimulates PAR₁-mediated plasma extravasation in vivo.

Technical Data:

M.Wt:	647.82
Formula:	C₃₁H₅₃N₉O₆
Storage:	Desiccate at -20°C
CAS No:	[197794-83-5]

Resources:

Certificate of Analysis / MSDS:

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References:

Hollenberg et al (1997) Proteinase-activated receptors: structural requirements for activity, receptor cross-reactivity, and receptor selectivity of receptor-activating peptides. Can.J.Physiol.Pharmacol. 75 832. Kawabata et al (2000) Characterization of the protease-activated receptor-1-mediated contraction and relaxation in the rat duodenal smooth muscle. Life Sci. 67 2521. de Garavilla et al (2001) Agonists of proteinase-activated receptor 1 induce plasma extravasation by a neurogenic mechanism. Br.J.Pharmacol. 133 975.

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Keywords: TFLLR-NH2, Peptides (Cardiovascular), PAR1-activating Peptide, Tocris Bioscience

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