Sulfisoxazole | Peptides (Cardiovascular) | Endothelin ETA Antagonist

Category:

Cat.No.	Product Name
0731	Sulfisoxazole

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Sulfisoxazole

Chemical Name: 4-Amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide

Biological Activity:

A selective ET_A endothelin receptor antagonist (IC₅₀ values are 600 and 2200 nM for ET_Aand ET_B receptors respectively).

Technical Data:

M.Wt:	267.3
Formula:	C₁₁H₁₃N₃O₃S
Storage:	Store at RT
Solubility:	Soluble to 100 mM in DMSO
Purity:	>99%
CAS No:	[127-69-5]

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis: View current batch

Product/Material Safety Data Sheet: View current batch

References:

Chan et al (1994) Identification of a new class of ET_A selective endothelin antagonists by pharmacophore directed screening. Biochem.Biophys.Res.Comm. 201 228.

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Keywords: Sulfisoxazole, Peptides (Cardiovascular), Endothelin ETA Antagonist, Tocris Bioscience

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