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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowGlycine Receptors
Cat.No. Product Name
2785 Strychnine hydrochloride
Price and Availability

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Strychnine
Chemical Name: Strychnidin-10-one hydrochloride

Biological Activity:

Competitive glycine receptor antagonist; convulsant. Also nicotinic receptor antagonist; displays competitive antagonism at α7 receptors and non-competitive antagonism at α4β2 receptors.

Technical Data:

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M.Wt: 370.87
Formula: C21H22N2O2.HCl
Storage: Store at RT
Solubility: Soluble to 50 mM in Water
Purity: >99%
CAS No: [1421-86-9]

Resources:

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    • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Mataubayashi et al (1998) Strychnine: a potent competitive antagonist of α-bungarotoxin-sensitive nicotinic acetylcholine receptors in rat hippocampal neurons. J.Pharmacol.Exp.Ther. 284 904. Betz et al (2006) Glycine receptors: recent insights into their structural organization and functional diversity. J.Neurochem. 67 1600.
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    Keywords: Strychnine, Ligand-gated Ion Channels, Competitive Glycine Receptor Antagonist, Tocris Bioscience
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