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Category: Nuclear ReceptorsarrowMineralocorticoid Receptor
Cat.No. Product Name
2968 Spironolactone
Alternative name(s): SC 9420
Aldactone
Price and Availability

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Spironolactone
Chemical Name: (7a,17a)-7-(Acetylthio)-17-hydroxy-3-oxopregn-4-ene-21- carboxylic acid g-lactone

Biological Activity:

Competitive mineralocorticoid (aldosterone) receptor antagonist. Antihypertensive.

Technical Data:

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M.Wt: 416.57
Formula: C24H32O4S
Storage: Store at RT
Solubility: Soluble to 100 mM in DMSO and to 50 mM in Ethanol
Purity: >98%
CAS No: [52-01-7]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Delyani et al (2000) Mineralocorticoid receptor antagonists: the evolution of utility and pharmacology. Kidney Int. 57 1408.
    View related products by Pharmacological Action or by Research Area

    Keywords: Spironolactone, Mineralocorticoid Receptor, Mineralocorticoid Receptor Antagonist, SC 9420, Aldactone, Tocris Bioscience

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