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Category: 7TM ReceptorsarrowAcetylcholine (Muscarinic) ReceptorsarrowAntagonists
Cat.No. Product Name
1414 Scopolamine hydrobromide
Price and Availability

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Scopolamine hydrobromide
Chemical Name: (a,S)-a-(Hydroxymethyl)benzeneacetic acid (1a,2b,4b,5a,7b)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02, 4]non-7-yl ester hydrobromide

Biological Activity:

Non-selective muscarinic antagonist. Widely used clinically to treat motion sickness.

Technical Data:

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M.Wt: 384.27
Formula: C17H21NO4.HBr
Storage: Store at RT
Solubility: Soluble to 100 mM in Water
Purity: >99%
CAS No: [114-49-8]

Resources:

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    References:

    Parkes (1965) An examination of central actions characteristic of scopolamine: comparison of central and peripheral activity in scopolamine, atropine and some synthetic basic esters. Psychopharmacologia 7 1. Nakao et al (1999) Cerebral blood flow responses to somatosensory stimulation are unaffected by scopolamine in unanesthetized rat. J.Pharmacol.Exp.Ther. 290 929. Jones and Shannon (2000) Effects of scopolamine in comparison with apomorphine and phencyclidine on prepulse inhibition in rats. Eur.J.Pharmacol. 391 105.
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    Keywords: Scopolamine Hydrobromide, Acetylcholine (Muscarinic) Receptors, Non-selective Muscarinic Antagonist, Tocris Bioscience

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