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Category: 7TM ReceptorsarrowPeptides (Cardiovascular)arrowEndothelin ReceptorsarrowOther Endothelin Receptor Compounds
Cat.No. Product Name
1899 Sarafotoxin S6a
Price and Availability

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Sarafotoxin S6a

Biological Activity:

Endothelin receptor agonist (EC50 values are 7.5 and > 150 nM for contraction of pig coronary artery and guinea pig aorta respectively). Nociceptive in vivo.

Technical Data:

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M.Wt: 2514.85
Formula: C105H156N28O34S5
Storage: Desiccate at -20°C
CAS No: [126738-34-9]

Resources:

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    References:

    Minkes et al (1992) Comparison of responses to sarafotoxins 6a and 6c in pulmonary and systemic vascular beds. Am.J.Physiol. 262 H852. Schoeffter and Randriantsoa (1993) Differences between endothelial receptors mediating contraction of guinea-pig aorta and pig coronary artery. Eur.J.Pharmacol. 249 199. Raffa et al (1996) Endothelin-induced nociception in mice: mediation by ETA and ETB receptors. J.Pharmacol.Exp.Ther. 276 47.
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    Keywords: Sarafotoxin S6a, Peptides (Cardiovascular), Endothelin Receptor Agonist, Tocris Bioscience
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