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Category: Ion ChannelsarrowLigand-gated Ion Channelsarrow5-HT3 ReceptorsarrowAgonists
Cat.No. Product Name
1205 SR 57227 hydrochloride
Price and Availability

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SR 57227 hydrochloride
Chemical Name: 1-(6-Chloro-2-pyridinyl)-4-piperidinamine hydrochloride

Biological Activity:

A high affinity, selective 5-HT3 receptor agonist, active in vivo and CNS penetrant.

Technical Data:

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M.Wt: 248.15
Formula: C10H15Cl2N3.HCl
Storage: Store at RT
Solubility: Soluble to 50 mM in Water
Purity: >99%
CAS No: [77145-61-0]

Resources:

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    • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Bachy et al (1993) SR 57227A: a potent and selective agonist at central and peripheral 5-HT3 receptors in vitro and in vivo. Eur.J.Pharmacol. 237 299. Edwards et al (1996) 5-HT3-like receptors in the rat medial prefrontal cortex: further pharmacological characterization. Brain Res. 733 21.
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    Keywords: SR 57227 Hydrochloride, Ligand-gated Ion Channels, Potent, Selective 5-HT3 Agonist, SR57227 Hydrochloride, Tocris Bioscience
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