SNC 80 | Opioid Receptors | Highly Selective Non-peptide D Agonist | SNC80

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Cat.No.	Product Name
0764	SNC 80

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SNC 80

Chemical Name: (+)-4-[(aR)-a-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazin yl)-3-methoxybenzyl]-N,N-diethylbenzamide

Biological Activity:

A highly selective and potent non-peptide δ-opioid agonist, 2000-fold selective over μ-opioid receptors.

Technical Data:

M.Wt:	449.64
Formula:	C₂₈H₃₉N₃O₂
Storage:	Store at RT
Solubility:	Soluble to 100 mM in 1eq. HCl and to 10 mM in DMSO
Purity:	>98%
CAS No:	[156727-74-1]

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Certificate of Analysis / MSDS:

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References:

Calderon et al (1994) Probes for narcotic receptor mediated phenomena. 19. Synthesis of (+)-4-[(αR)-α-((2S,5R)-4-allyl-2,5-dimethyl-1-piperazinyl)-3-methoxybenzyl]-N,N-diethylbenzamide (SNC80): a highly selective nonpeptide δ opioid receptor agonist. J.Med.Chem. 37 2125. Bilsky et al (1995) SNC 80, a selective, nonpeptidic and systemically active opioid delta agonist. J.Pharmacol.Exp.Ther. 273 359. Knapp et al (1996) Structure-activity relationships for SNC80 and related compounds at cloned human delta and mu opioid receptors. J.Pharmacol.Exp.Ther. 277 1284.

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Keywords: SNC 80, Opioid Receptors, Highly Selective Non-peptide D Agonist, SNC80, Tocris Bioscience

Literature in this Area

Scientific Reviews

Opioid Receptors
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