(+)-SK&F 10047 Hydrochloride | Sigma & Imidazoline | S1 Selective Agonist | SK&F 10047 Hydrochloride

Category:

Cat.No.	Product Name
1079	(+)-SK&F 10047 hydrochloride

Price and Availability

Click here for full price details of
(+)-SK&F 10047 hydrochloride

Chemical Name: [2S-(2a,6a,11R*]-1,2,3,4,5,6-hexahydro-6,11-dimethyl-3- (2-propenyl)-2,6-methano-3-benzazocin-8-ol hydrochloride

Biological Activity:

Prototypical σ₁ receptor agonist. Behaviourally active in animal models of memory and stress.

Technical Data:

M.Wt:	293.84
Formula:	C₁₇H₂₃NO.HCl
Storage:	Desiccate at +4°C
Solubility:	Soluble to 100 mM in Water
Purity:	>98%
CAS No:	[58640-82-7]

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis: View current batch

For specific/earlier batch please select:

Product/Material Safety Data Sheet: View current batch

For specific/earlier batch please select:

References:

Walker et al (1990) Sigma receptors: biology and function. Pharmacol.Rev. 42 355. Matsuno et al (1995) Involvement of σ₁ receptor in (+)-N-allylnormetazocine-stimulated hippocampal cholinergic functions in rats. Brain Res. 690 200. Kamei et al (1996) (+)-SKF-10,047 and dextromethorphan ameliorate conditioned fear stress via dopaminergic systems linked to phenytoin-regulated σ₁sites. Eur.J.Pharmacol. 309 149.

View related products by Pharmacological Action or by Research Area

Keywords: (+)-SK&F 10047 Hydrochloride, Sigma & Imidazoline, S1 Selective Agonist, SK&F 10047 Hydrochloride, Tocris Bioscience

New Product Guide

	Our latest New Product Guide highlights over 140 new products.
Request Copy / View PDF

Spring Specials

25% discount* on
selected Tocris products including:

Potent & selective NOP antagonist
Blocker of retinoic acid metabolism
Potent CCR1 receptor antagonist
Selective GnRH receptor antagonist
NMDA receptor antagonist

*Terms and conditions

New Products in this Area

	2669	TC 1
	High affinity σ₁ ligand
	2562	PB 28 dihydrochloride
	High affinity σ₂ agonist

for new product e-alerts

User ID
Password