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Category: 7TM ReceptorsarrowDopamine ReceptorsarrowD1-like Receptors
Cat.No. Product Name
1447 SKF 81297 hydrobromide
Price and Availability

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SKF 81297
Chemical Name: 6-Chloro-2,3,4,5-tetrahydro-1-phenyl-1H-3-benzazepine hydrobromide

Biological Activity:

Dopamine D1-like receptor agonist. Centrally active following systemic administration in vivo.

Technical Data:

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M.Wt: 370.67
Formula: C16H16ClNO2.HBr
Storage: Desiccate at +4°C
Solubility: Soluble to 100 mM in DMSO
Purity: >98%
CAS No: [71636-61-8]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Arnt et al (1988) Relative dopamine D1 and D2 receptor affinity and efficacy determine whether dopamine agonists induce hyperactivity or oral stereotypy in rats. Pharmacol.Toxicol. 62 121. Peacock et al (1990) The effects of dopamine D1 and D2 receptor agonists and antagonists in monkeys withdrawn from long-term neuroleptic treatment. Eur.J.Pharmacol. 186 49. Reavill et al (1993) Pharmacological characterization of the discriminative stimulus properties of the dopamine D1 agonist, SKF 81297. Behav.Pharmacol. 4 135.
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    Keywords: SKF 81297, Dopamine Receptors, D1 Agonist, SKF81297, Tocris Bioscience

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