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Category: Cellular Processes and ComponentsarrowCell MetabolismarrowAmyloid Beta Peptides
Cat.No. Product Name
2408 Ro 90-7501
Price and Availability

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Ro 90-7501
Chemical Name: 2'-(4-Aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine

Biological Activity:

Inhibitor of amyloid β42 (Ab42) fibril assembly; reduces Aβ42-induced toxicity (EC50 = 2 μM).

Technical Data:

Click here for more information on batch specific data
M.Wt: 340.39
Formula: C20H16N6
Storage: Store at +4°C
Solubility: Soluble to 10 mM in 1eq. HCl and to 100 mM in DMSO
Purity: >99%
CAS No: [293762-45-5]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Bohrmann et al (2000) Self-assembly of β-amyloid 42 is retarded by small molecular ligands at the stage of structural intermediates. J.Struct.Biol. 130 232.
    View related products by Pharmacological Action or by Research Area

    Keywords: Ro 90-7501, Cell Metabolism, Inhibitor Of Ab42 Fibril Formation, Ro90-7501, Tocris Bioscience

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