Resveratrol | Oxygenases / Oxidases | Cyclooxygenase Inhibitor

Category:

Cat.No.	Product Name
1418	Resveratrol

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Resveratrol

Chemical Name: 5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3,benzenediol

Biological Activity:

A phytoestrogen with antitumour, antioxidant, antiplatelet, anti-inflammatory and antifungal effects. Inhibits cytochrome P450 1A1 (IC₅₀ = 23 μM) and displays mixed agonist/antagonist actions at ERα and ERβ estrogen receptors.

Technical Data:

M.Wt:	228.25
Formula:	C₁₄H₁₂O₃
Storage:	Desiccate at +4°C
Solubility:	Soluble to 100 mM in Ethanol and to 100 mM in DMSO
Purity:	>98%
CAS No:	[501-36-0]

Resources:

Certificate of Analysis / MSDS:

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References:

Kimura et al (1985) Effects of stilbenes on arachidonate metabolism in leukocytes. Biochim.Biophys.Acta 834 275. Chun et al (1999) Resveratrol is a selective human cytochrome P450 1A1 inhibitor. Biochem.Biophys.Res.Comm. 262 20. Fremont (2000) Biological effects of resveratrol. Life Sci. 66 663. Bowers et al (2000) Resveratrol acts as a mixed agonist/antagonist for estrogen receptors alpha and beta. Endocrinology 141 3657. Baur and Sinclair (2006) Therapeutic potential of reservatrol: the in vivo evidence. Nat.Rev. 5 493.

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Keywords: Resveratrol, Oxygenases / Oxidases, Cyclooxygenase Inhibitor, Tocris Bioscience

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