RU 26752 | Mineralocorticoid Receptor | Mineralocorticoid Receptor Antagonist | RU26752

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Cat.No.	Product Name
2970	RU 26752

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RU 26752

Chemical Name: (7a,17a)-17-Hydroxy-3-oxo-7-propylpregn-4-ene-21-carbox ylic acid g-lactone

Biological Activity:

Mineralocorticoid receptor antagonist. Prevents aldosterone-induced hypertension in rats.

Technical Data:

M.Wt:	384.55
Formula:	C₂₅H₃₆O₃
Storage:	Store at -20°C
Solubility:	Soluble to 25 mM in DMSO
Purity:	>99%
CAS No:	[76676-33-0]

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis: View current batch

Product/Material Safety Data Sheet: View current batch

References:

Lazar and Agarwal (1986) Evidence for an antagonist specific receptor that does not bind mineralocorticoid agonists. Biochem.Biophy.Res.Comms. 134 261. Kalimi et al (1990) Effects of antimineralocorticoid RU 26752 on steroid-induced hypertension in rats. Am.J.Physiol. 258 E737. Huyet et al (2007) Structural basis of spirolactone recognition by the mineralocorticoid receptor. Mol.Pharmacol. 72 563.

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Keywords: RU 26752, Mineralocorticoid Receptor, Mineralocorticoid Receptor Antagonist, RU26752, Tocris Bioscience

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