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Category: Ion ChannelsarrowLigand-gated Ion Channelsarrow5-HT3 ReceptorsarrowOther 5-HT3
Cat.No. Product Name
1015 RS 16566 dihydrochloride
Price and Availability

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RS 16566 dihydrochloride

Other Information:

Sold with the permission of Roche Bioscience
Chemical Name: (R)-N-1-Azabicyclo[2.2.2]oct-3-yl-6-chloro-1-(1-methyle thyl)-1H-benzimidazole-4-carboxamide

Biological Activity:

High affinity ligand for the (R)-zacopride binding site (pKi 9.84 ).

Technical Data:

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M.Wt: 419.78
Formula: C18H23ClN4O.2HCl
Storage: Store at RT
Solubility: Soluble to 10 mM in Water
Purity: >98%
CAS No: [175729-69-8]

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    References:

    Flippen et al (1996) (R)-3-(6-Chloro-1-isopropylbenzimidazole-4-carboxamido)quinuclidine: a high affinity ligand for the (R)-zacopride binding site. Bioorg.Med.Chem.Lett. 6 477.

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    Keywords: RS 16566 Dihydrochloride, Ligand-gated Ion Channels, 5-HT3 Ligand. Also Shows Affinity For Zacopride Binding Site, RS16566 Dihydrochloride, Tocris Bioscience
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