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Category: Ion ChannelsarrowLigand-gated Ion Channelsarrow5-HT3 ReceptorsarrowAgonists
Cat.No. Product Name
0629 Quipazine dimaleate  
Price and Availability

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Quipazine dimaleate
Chemical Name: 2-(1-Piperazinyl)quinoline dimaleate

Biological Activity:

Selective 5-HT3 receptor agonist. Also displays antagonist activity at peripheral 5-HT3 receptors. [3H]-Quipazine labels 5-HT3 sites in the cortical membranes.

Technical Data:

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M.Wt: 445.43
Formula: C13H15N3.2C4H4O4
Storage: Store at RT
Solubility: Soluble to 100 mM in Water
CAS No: [5786-68-5]

Resources:

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    • Certificate of Analysis / MSDS:

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    Product/Material Safety Data Sheet: View current batch

    References:

    Ireland and Tyers (1987) Pharmacological characterization of 5-hydroxytryptamine-induced depolarization of the rat isolated vagus nerve. Br.J.Pharmacol. 90 229. Peroutka and Hamik (1988) [3H]Quipazine labels 5-HT3 recognition sites in rat cortical membranes. Eur.J.Pharmacol. 148 297. Sharif et al (1991) Characteristics of 5-HT3 binding sites in NG108-15, NCB-20 neuroblastoma cells and rat cerebral cortex using [3H]-quipazine and [3H]-GR65630 binding. Br.J.Pharmacol. 102 919.
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    Keywords: Quipazine Dimaleate, Ligand-gated Ion Channels, 5-HT3 Agonist, Tocris Bioscience
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