Prazosin Hydrochloride | Adrenergic Receptors | A1 Antagonist. MT3 Antagonist

Category:

Cat.No.	Product Name
0623	Prazosin hydrochloride

Price and Availability

Click here for full price details of
Prazosin hydrochloride

Chemical Name: 1-(4-Amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furanylca rbonyl)piperazine hydrochloride

Biological Activity:

α₁ and α_2B-adrenoceptor antagonist. Also a potent antagonist at the melatonin MT₃ receptor (K_i = 10.2 nM).

Technical Data:

M.Wt:	419.87
Formula:	C₁₉H₂₁N₅O₄.HCl
Storage:	Store at RT
Solubility:	Soluble to 25 mM in DMSO and to 5 mM in Ethanol
Purity:	>99%
CAS No:	[19237-84-4]

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis: View current batch

For specific/earlier batch please select:

Product/Material Safety Data Sheet: View current batch

For specific/earlier batch please select:

References:

Merck Index 12 7897. Pickering and Niles (1990) Pharmacological characterization of melatonin binding sites in Syrian hamster hypothalamus. Eur.J.Pharmacol. 175 71. Mathe et al (1996) Prazosin inhibits MK-801-induced hyperlocomotion and dopamine release in the nucleus accumbens. Eur.J.Pharmacol. 309 1. Paul et al (1999) Characterisation of 2-[¹²⁵I]iodomelatonin binding sites in syrian hamster peripheral organs. J.Pharmacol.Exp.Ther. 290 334.

View related products by Pharmacological Action or by Research Area

Keywords: Prazosin Hydrochloride, Adrenergic Receptors, A1 Antagonist. MT3 Antagonist, Tocris Bioscience

Literature in this Area

Scientific Reviews

Adrenoceptor Pharmacology
Download PDF

Products You Can Trust

When you buy a product from Tocris you know you are buying the genuine article.

If we supply a patented product we will always seek to obtain a licence from the patent holder and ensure that our product meets or exceeds specifications.

Our reputation for integrity and uncompromising quality allows us to partner with world-class scientific organisations to bring novel and exclusive products to market.

New Products in this Area

	2964	Doxazosin mesylate
	α₁-adrenoceptor antagonist
	1051	Zinterol hydrochloride
	Selective β₂ agonist
	2958	DSP-4
	Adrenergic neurotoxin
	2838	(R)-(-)-Phenylephrine hydrochloride
	α₁-adrenoceptor agonist
	2806	Alprenolol hydrochloride
	β antagonist
	2398	SNAP 5089
	Subtype selective α_1A-adrenoceptor antagonist
	2638	ST 91
	α₂ agonist, putative α_2C agonist
	2685	Carvedilol
	β-adrenoceptor and α₁-adrenoceptor antagonist
	2658	Bucindolol
	β₁- and β₂-adrenoceptor antagonist
	2666	JP 1302 dihydrochloride
	Potent and selective α_2C antagonist
	1811	Modafinil
	Psychostimulant

for new product e-alerts

User ID
Password