|
Category:
|
7TM Receptors Acetylcholine (Muscarinic) ReceptorsAntagonists
|
|
Cat.No.
|
Product Name
|
|
1071 |
Pirenzepine dihydrochloride
|
|
|
|
Price and Availability
Click here for full price details of
Pirenzepine dihydrochloride
|
|
Chemical Name:
5,11-Dihydro-11-[(4-methyl-1-piperazinyl)acetyl]-6H-pyr
ido[2,3-b][1,4]benzodiazepin-6-one dihydrochloride |
|
|
Biological Activity:
M1 muscarinic receptor selective antagonist. Inverse
agonist activity reported.
|
Technical Data:
|
|
|
Resources:
|
|
Certificate of Analysis / MSDS:
|
For specific/earlier batch please select:
|
For specific/earlier batch please select:
|
|
References:
Hammer et al (1980) Pirenzepine distinguishes between different
subclasses of muscarinic receptors. Nature 283 90. Doods et
al (1994) Pharmacological profile of selective muscarinic receptor
antagonists on guinea-pig ileal smooth muscle. Eur.J.Pharmacol. 253
275. Eglen et al (1996) Muscarinic receptor subtypes and smooth
muscle function. Pharmacol.Rev. 48 531. Daeffler et al
(1999) Inverse agonist activity of pirenzepine at M2 muscarinic
acetylcholine receptors. Br.J.Pharmacol. 126 1246.
|
|
View related products by Pharmacological Action
or by Research Area
Keywords: Pirenzepine Dihydrochloride, Acetylcholine (Muscarinic) Receptors, Selective M1 Muscarinic Antagonist, Tocris Bioscience
|
|
|
