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Category: EnzymesarrowPhosphodiesterases
Cat.No. Product Name
3056 Pentoxifylline
Alternative name(s): PTX
Price and Availability

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Pentoxifylline
Chemical Name: 3,7-Dimethyl-1-(5-oxohexyl)xanthine

Biological Activity:

Phosphodiesterase inhibitor that blocks production of TNF-α and other cytokines. Displays antinociceptive activity.

Technical Data:

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M.Wt: 278.31
Formula: C13H18N4O3
Storage: Store at RT
Solubility: Soluble to 100 mM in Water
Purity: >99%
CAS No: [6493-05-6]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Monshouwer et al (1996) Differential effect of pentoxifylline on lipopolysaccharide-induced downregulation of cytochrome P450. 52 1195. Vale et al (2004) Antihyperalgesic effect of pentoxifylline on experimental inflammatory pain. Br.J.Pharmacol. 143 833.
    View related products by Pharmacological Action or by Research Area

    Keywords: Pentoxifylline, Phosphodiesterases, PDE Inhibitor, PTX, Tocris Bioscience

    Literature in this Area
    Signal Transduction Guide
    Signal Transduction Guide : An informative guide for all scientists working in: Cell cycle & apoptosis, Protein kinases & phosphatases, Ion channels, Calcium & lipid signaling, Cyclic nucleotides & G-proteins, Nitric oxide, & Signaling EnzymesA complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
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