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Category: 7TM ReceptorsarrowDopamine ReceptorsarrowDopaminergic-Related
Cat.No. Product Name
3045 Pemoline
Alternative name(s): Phenoxazole
Phenylisohydantoin
Price and Availability

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pemoline

Other Information:

This is a controlled substance with associated conditions of supply; the relevent licence/documentation from the appropriate governing body will be required.
Chemical Name: 2-Amino-5-phenyl-4(5H)-oxazolone

Biological Activity:

Long-acting central stimulant that induces self-injurious behaviour in rats. Acts as an indirect monoamine agonist.

Technical Data:

Click here for more information on batch specific data
M.Wt: 176.17
Formula: C9H8N2O2
Storage: Store at RT
Solubility: Soluble to 10 mM in Ethanol
Purity: >99%
CAS No: [2152-34-3]

Resources:

  • Certificate of Analysis / MSDS:

    Certificate of Analysis: View current batch
    Product/Material Safety Data Sheet: View current batch

    References:

    Mueller and Nyhan (1982) Pharmacologic control of pemoline induced self-injurious behavior in rats. Pharmacol.Biochem.Behav. 16 957. Kies and Devine (2004) Self-injurious behaviour: a comparison of caffeine and pemoline models in rats. Pharmacol.Biochem.Behav. 79 587. Muehlmann et al (2008) Pemoline (2-Amino-5-phenyl-1,3-oxazol-4-one)-induced self-injurious behavior: a rodent model of pharmacotherapeutic efficacy. J.Pharmacol.Exp.Ther. 324 214.
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    Keywords: Pemoline, Dopamine Receptors, CNS Stimulant, Indirect Monoamine Agonist, Phenoxazole, Phenylisohydantoin, Tocris Bioscience

    Literature in this Area
    Scientific Reviews
    Dopamine Receptors
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    Tocris is to be congratulated for continuing to meet the current demand for a rapid and reliable source of high-quality compounds that are urgently needed as pharmacological tools by a growing international population of cannabinoid researchers..”
    Researcher, University of Aberdeen, UK
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