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Category: Ion ChannelsarrowLigand-gated Ion ChannelsarrowAcetylcholine (Nicotinic) ReceptorsarrowAntagonists
Cat.No. Product Name
0693 Pancuronium dibromide  
Price and Availability

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Pancuronium dibromide
Chemical Name: 1,1'-(3a,17b-Dihydroxy-2b,5a-androstan-2b,16b-ylene) bis[1-methylpiperidinium] diacetate dibromide

Biological Activity:

Nicotine (neuromuscular) antagonist. Skeletal muscle relaxant.

Technical Data:

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M.Wt: 732.68
Formula: C35H60Br2N2O4
Storage: Desiccate at RT
Solubility: Soluble to 100 mM in Water and to 100 mM in DMSO
Purity: >99%
CAS No: [15500-66-0]

Resources:

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    References:

    Merck 12 7139. Fryer and Maclagan (1987) Pancuronium and gallamine are antagonists for pre- and post-junctional muscarinic receptors in the guinea-pig lung. Naunyn-Schmied.Arch.Pharmacol. 335 367. Maestrone et al (1994) Extracellular pancuronium affects sodium current in chick embryo sensory neurones. Br.J.Pharmacol. 111, 283. Lowenick et al (2001) Open channel and competitive block of nicotinic receptors by pancuronium and atracurium. Eur.J.Pharmacol. 413 31.
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    Keywords: Pancuronium Dibromide, Ligand-gated Ion Channels, Nicotinic (neuromuscular) Antagonist , Tocris Bioscience
    Literature in this Area
    Scientific Reviews
    Nicotinic ACh Receptors
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    Signal Transduction Guide
    Signal Transduction Guide : An informative guide for all scientists working in: Cell cycle & apoptosis, Protein kinases & phosphatases, Ion channels, Calcium & lipid signaling, Cyclic nucleotides & G-proteins, Nitric oxide, & Signaling EnzymesA complete listing of signal transduction products available from Tocris, including descriptions on selected tools and unit sizes.
    View PDF
    Product Feature
    Nicotinic Receptors
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