PP 3 | Kinases | Negative Control For PP 2 (Cat. No. 1407) | PP3

Category:

Cat.No.	Product Name
2794	PP 3

Price and Availability

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PP 3

Chemical Name: 1-Phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine

Biological Activity:

Negative control for the src kinase inhibitor PP 2 (Cat. No. 1407). Inhibits EGFR kinase (IC₅₀= 2.7 μM).

Technical Data:

M.Wt:	211.22
Formula:	C₁₁H₉N₅
Storage:	Store at -20°C
Solubility:	Soluble to 100 mM in DMSO and to 25 mM in Ethanol
CAS No:	[5334-30-5]

Resources:

Certificate of Analysis / MSDS:

Certificate of Analysis: View current batch

Product/Material Safety Data Sheet: View current batch

References:

Traxler et al (1997) Use of a pharmacophore model for the design of EGF-R tyrosine kinase inhibitors: 4-(phenylamino)pyrazolo[3,4-d]pyrimidines. J.Med.Chem. 40 3601. Hou et al (2007) PP2, a potent inhibitor of Src family kinases, protects against hippocampal CA1 pyramidal cell death after transient global brain ischemia. Neurosci.Letts. 420 235.

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Keywords: PP 3, Kinases, Negative Control For PP 2 (Cat. No. 1407), PP3, Tocris Bioscience

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