(+)-PD 128907 Hydrochloride | Dopamine Receptors | D3 Agonist (D3 ³ D2 > D4) | PD128907 Hydrochloride

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Cat.No.	Product Name
1243	(+)-PD 128907 hydrochloride

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(+)-PD 128907 hydrochloride

Chemical Name: (4aR,10bR)-3,4a,4,10b-Tetrahydro-4-propyl-2H,5H-[1]benz opyrano-[4,3-b]-1,4-oxazin-9-ol hydrochloride

Biological Activity:

Potent D₃ dopamine receptor agonist (K_i = 2.3 nM). Displays 18-200-fold selectivity over other dopamine receptor subtypes.

Technical Data:

M.Wt:	285.77
Formula:	C₁₄H₁₉NO₃.HCl
Storage:	Desiccate at +4°C
Solubility:	Soluble to 10 mM in Water
Purity:	>99%
CAS No:	[300576-59-4]

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References:

Pugsley et al (1995) Neurochemical and functional characterization of the preferentially selective dopamine D₃ agonist PD 128907. J.Pharmacol.Exp.Ther. 275 1355. Bristow et al (1996) The behavioural and neurochemical profile of the putative dopamine D₃ receptor agonist, (+)-PD 128907, in the rat. Neuropharmacology 35 285. Witkin et al (1998) Atypical antipsychotic-like effects of the dopamine D₃ receptor agonist (+)-PD 128907. Eur.J.Pharmacol. 347 R1.

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Keywords: (+)-PD 128907 Hydrochloride, Dopamine Receptors, D3 Agonist (D3 ³ D2 > D4), PD128907 Hydrochloride, Tocris Bioscience

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Dopamine Receptors
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