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Category:
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7TM Receptors PAF Receptors
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Cat.No.
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Product Name
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2940 |
PAF (C16)
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| Alternative name(s): |
Platelet-activating factor |
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Price and Availability
Click here for full price details of
PAF (C16)
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Chemical Name:
(7R)-7-(Acetyloxy)-4-hydroxy-N,N,N-trimethyl-3,5,9-trio
xa-4-phosphapentacosan-1-aminium-4-oxide |
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Biological Activity:
Endogenous platelet-activating
factor (PAF) and ligand for PAF receptors. Produced by inflammatory cells and
is a potent chemoattractant for polymorphonuclear neutrophils. Induces
increased vascular permeability.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Oda et
al (1985) Molecular species of platelet-activating factor generated by
human neutrophils challenged with ionophore A23187. J.Immunol. 134
1090. Archer et al (1988) Actions of platelet activating factor
(PAF) homologues and their combinations on neutrophil chemokinesis and
cutaneous inflammatory responses in man. J.Invest.Dermatol. 91
82. Handa et al (1991) Vasorelaxant effect of C16-PAF
and C18-PAF on renal blood flow and systemic blood pressure in the
anesthetized rat. Life Sci. 49 747.
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View related products by Pharmacological Action
or by Research Area
Keywords: PAF (C16), PAF Receptors, Endogenous Platelet-activating Factor (PAF), Platelet-activating Factor, PAF(C16), Tocris Bioscience
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