Ouabain | ATPases / GTPases | Na+,K+-ATPase Inhibitor

Category:

Cat.No.	Product Name
1076	Ouabain

Price and Availability

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Ouabain

Chemical Name: 3-[(6-Deoxy-a-L-mannopyranosyl)oxy]-1,5,11a,14,19-penta hydoxycard-20(22)-enolide

Biological Activity:

Selective Na⁺, K⁺-ATPase inhibitor.

Technical Data:

M.Wt:	584.66
Formula:	C₂₉H₄₄O₁₂
Storage:	Desiccate at -20°C
Solubility:	Soluble to 50 mM in Ethanol and to 10 mM in Water
CAS No:	[630-60-4]

Resources:

Certificate of Analysis / MSDS:

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References:

Merck Index 12 7031. Croyle et al (1997) Extensive random mutagenesis analysis of the Na/K⁺ ATPase alpha subunit identifies known and previously unidentified amino acid residues that alter ouabain sensitivity-implications for ouabain binding. Eur.J.Biochem. 248 488. Marjorie et al (1997) Ouabain improves cardiac function in vivo in rats with heart failure after chronic but not acute treatment. Naunyn-Schmied.Arch.Pharmacol. 356 203. Hosoi et al (1997) Isoform-specific up-regulation by ouabain of Na⁺, K⁺-ATPase in cultured rat astrocytes. J.Neurochem. 69 2189.

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Keywords: Ouabain, ATPases / GTPases, Na+,K+-ATPase Inhibitor, Tocris Bioscience

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