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Category:
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7TM Receptors Peptides (Neuropeptides)Other Neuropeptides
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Biological Activity:
Anorexigenic
peptide hormone derived from the same prepropeptide as ghrelin. Decreases food
intake, gastric emptying, jejunal contraction and weight gain in rats by
binding to orphan G-protein-coupled receptor GPR39. Active following systemic
administration.
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Technical Data:
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Resources:
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Certificate of Analysis / MSDS:
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References:
Zhang et al (2005) Obestatin,
a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food
intake. Science 310
996. Nogueiras and Tschop (2005) Biomedicine. Separation of conjoined
hormones yields appetite rivals. Science 310 985. Pan and
Kastin (2006) Differential BBB interactions of three ingestive peptides:
obestatin, ghrelin, and adiponectin. Peptides 27 911.
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View related products by Pharmacological Action
or by Research Area
Keywords: Obestatin (rat), Peptides (Neuropeptides), Endogenous Anorexigenic Peptide, Tocris Bioscience
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