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Category: Ion ChannelsarrowTransient Receptor Potential ChannelsarrowTRPV
Cat.No. Product Name
1641

OLDA

Alternative name(s): N-Oleoyldopamine
Price and Availability

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OLDA
Chemical Name: (9Z)-N-[2-(3,4-Dihydroxyphenyl)ethyl]-9-octadecenamide

Biological Activity:

Potent endogenous vanilloid TRPV1 (VR1) receptor agonist (EC50 = 36 nM at hVR1) with low affinity for rCB1 receptors (Ki = 1.6 μM). Potently induces VR1-mediated thermal hyperalgesia in rats in vivo.

Technical Data:

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M.Wt: 417.63
Formula: C26H43NO3
Storage: Desiccate at -20°C
Solubility: Soluble to 50 mM in DMSO and to 50 mM in Ethanol
CAS No: [105955-11-1]

Resources:

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    References:

    Chu et al (2003) N-Oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia. J.Biol.Chem. 278 13633. Chu et al (2003) N-Oleoyldopamine, a novel endogenous capsaicin-like lipid that produces hyperalgesia. J.Biol.Chem. 278 13633. Butelman et al (2004) Anitallodynic effects of loperamide and fentanyl against topical capsaicin-induced allodynia in unanesthetized primates. J.Pharmacol.Exp.Ther. 311 155.
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    Keywords: OLDA, Transient Receptor Potential Channels, Potent, Selective Endogenous TRPV1 (VR1) Agonist, N-Oleoyldopamine, Tocris Bioscience

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