OBAA | Esterases | Phospholipase A2 Inhibitor

Category:

Cat.No.	Product Name
0606	OBAA

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OBAA

Chemical Name: 4-(4-Octadecylphenyl)-4-oxobutenoic acid

Biological Activity:

A potent inhibitor of phospholipase A₂(IC₅₀ = 70 nM). Reduces bronchospasm in guinea pigs in vivo.

Technical Data:

M.Wt:	428.65
Formula:	C₂₈H₄₄O₃
Storage:	Desiccate at +4°C
Solubility:	Soluble to 10 mM in DMSO

Resources:

Certificate of Analysis / MSDS:

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References:

Madi et al (1991) Allergen-induced bronchospasm in passively sensitized guinea-pigs - influence of new substances in comparison to reference compounds. Agents Actions 32 144. Kohler et al (1991) Phospholipase-A₂ inhibition by alkylbenzoyl acrylic acids. Agents Actions 32 70. Kohler et al (1992) Phospholipase A₂ inhibition by alkylbenzoyl acrylic acids. Biochem.Pharmacol. 44 805.

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Keywords: OBAA, Esterases, Phospholipase A2 Inhibitor, Tocris Bioscience

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