Nociceptin (1-13)NH2 | Opioid Receptors | Potent ORL1 Agonist

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Cat.No.	Product Name
1358	Nociceptin (1-13)NH₂

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Nociceptin (1-13)NH2

Biological Activity:

Bioactive metabolite of nociceptin and potent agonist for the ORL₁ receptor (pEC₅₀ = 7.9 in mouse vas deferens, K_i = 0.75 nM for binding to rat forebrain membranes).

Technical Data:

M.Wt:	1381.6
Formula:	C₆₁H₁₀₀N₂₂O₁₅
Storage:	Desiccate at -20°C
CAS No:	[178064-02-3]

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References:

Varani et al (1998) Nociceptin receptor binding in mouse forebrain membranes: thermodynamic characteristics and structure activity relationships. Br.J.Pharmacol. 125 1485. Calo et al (2000) Pharmacology of nociceptin and its receptor: a novel therapeutic target. Br.J.Pharmacol. 129 1261.

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Keywords: Nociceptin (1-13)NH2, Opioid Receptors, Potent ORL1 Agonist, Tocris Bioscience

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Opioid Receptors
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