Naftopidil Hydrochloride | Adrenergic Receptors | A1 Antagonist

Category:

Cat.No.	Product Name
0597	Naftopidil hydrochloride

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Naftopidil hydrochloride

Chemical Name: 4-(2-Methoxyphenyl)-a-[(1-naphthalenyloxy)methyl]-1-pip erazineethanol hydrochloride

Biological Activity:

An α₁-adrenoceptor antagonist with only weak antagonism at post-junctional α₂ receptors; a potent, persistent antihypertensive and vasodilator.

Technical Data:

M.Wt:	428.96
Formula:	C₂₄H₂₈N₂O₃.HCl
Storage:	Store at RT
Solubility:	Soluble to 100 mM in DMSO
Purity:	>98%
CAS No:	[57149-07 2]

Resources:

Certificate of Analysis / MSDS:

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References:

Borbe and Peter (1990) Alpha-1-adrenoceptor-binding material in rat plasma following single oral administration of naftopidil. Arzneim.Forsch. 40 253. Muramatsu et al (1991) Pharmacological profile of the novel alpha-adrenoceptor antagonist KT-611 (naftopidil). Jap.J.Pharmacol. 55 391.

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Keywords: Naftopidil Hydrochloride, Adrenergic Receptors, A1 Antagonist, Tocris Bioscience

Literature in this Area

Scientific Reviews

Adrenoceptor Pharmacology
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Purity To Rely On

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This accurate purity data is available on a batch-specific basis for every product via our website. At Tocris we work hard to ensure that we always supply to the highest possible standards of purity.

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