NPPB | Chloride Channels | Chloride Channel Blocker

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Cat.No.	Product Name
0593	NPPB

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NPPB

Chemical Name: 5-Nitro-2-(3-phenylpropylamino)benzoic acid

Biological Activity:

Very potent chloride channel blocker.

Technical Data:

M.Wt:	300.31
Formula:	C₁₆H₁₆N₂O₄
Storage:	Store at RT
Solubility:	Soluble to 100 mM in DMSO and to 100 mM in Ethanol
Purity:	>99%
CAS No:	[107254-86-4]

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References:

Wangemann et al (1986) Cl^--channel blockers in the thick ascending limb of the loop of Henle. Structure-activity relationship. Pflugers Arch. 407 S128. Keeling et al (1991) Effects of NPPB (5-nitro-1-(3-phenylpropylamino)benzoic acid on chloride transport in intestinal tissues and the T₈₄ cell line. Biochim.Biophys.Acta 115 42. Kirkup et al (1996) Investigation of the effects of 5-nitro-2-(3-phenylpropylamino)-benzoic acid (NPPB) on membrane currents in rat portal vein. Br.J.Pharmacol. 117 175.

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Keywords: NPPB, Chloride Channels, Chloride Channel Blocker, Tocris Bioscience

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